منابع مشابه
Why is WASID an important clinical trial?
Accessible online at: www.karger.com/ned Fifty years ago, coumarins (i.e. warfarin and other oral vitamin K antagonists) were first given for secondary prevention of ischemic stroke and were widely prescribed for this purpose during the subsequent decades despite the paucity of good evidence supporting their benefit, not unusual for neurological therapeutics of the era. More recently, it has be...
متن کاملPARADIGM-HF Trial and its Important Clinical Meanings
ACEi/ARB and ß blocker and aldosterone antagonist have been a gold standard for treating chronic heart failure with reduced ejection fraction (HFrEF). The paper described simply the PARADIGM-HF study (Prospective comparison of ARNi with ACEi to Determine Impact on Global Mortality and morbidity in HF trial), and the results showed that compared to enalapril, LCZ69(ARNi) significantly reduced th...
متن کاملDouble-blind controlled clinical trial of clofazimine in reactive phases of lepromatous leprosy.
A double-blind controlled trial in 24 lepromatous leprosy patients in reaction showed that clofazimine (Lamprene) controlled symptoms of erythema nodosum leprosum reaction in lepromatous leprosy better than prednisolone. Clofazimine also appeared to be significantly superior in preventing recurrence once the reaction had been controlled. There was a statistically significant rise in serum album...
متن کاملClinical epidemiology--how important now?
C hronic diseases have become an increasing portion of modern medicine in the Western world and the goals for treatment are not only to relieve symptoms and their influence on daily life for patients but also to avoid long term complications of the disease and of the treatment given. The rules for obtaining evidence of the benefit of a new treatment have been widely accepted, with the randomise...
متن کامل[Intention to treat and follow up are important in assessing validity of a randomized clinical trial].
In this randomized controlled multicenter trial, we compared endoscopic variceal banding ligation (VBL) with propranolol (PPL) for primary prophylaxis of variceal bleeding. One hundred fifty-two cirrhotic patients with 2 or more esophageal varices (diameter >5 mm) without prior bleeding were randomized to VBL (n=75) or PPL (n=77). The groups were well matched with respect to baseline characteri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Science
سال: 2016
ISSN: 2321-5291
DOI: 10.29387/ms.2016.4.1.303-307